The Purse Lab
Ani Shalamberidze, a Ph.D. JACS paper in collaboration with the Kleiner Lab at Princeton exhibits that a mix of judiciously selected fluorescent nucleoside analogues with genetic upregulation of nucleoside kinase activity allows metabolic labeling and live-cell imaging of RNA biology. The strategy has already been used to find beforehand unknown cytoplasmic RNA granules generated throughout oxidative stress. Nice ready for extra discoveries in RNA biology! Purse Lab Ph.D. pupil George Samaan has develop the primary fluorescent nucleobase analogue that performs robustly in single-molecule fluorescence measurements. Get prepared for thrilling new advances in single-molecule biophysical research on nucleic acids!
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